CA River Plate vs. Independiente Santa Fe

River Plate enters the Copa Sudamericana Round of 16 second leg at the Estadio Más Monumental holding a strong implied probability edge after a 0-0 first-leg draw in Bogotá, where Santa Fe created clearer chances but failed to convert. River’s home record, recent 2-0 league win over Argentinos Juniors, and additions like Thiago Almada support trader consensus around a home victory, even with absences of Marcos Acuña, Gonzalo Montiel, and Sebastián Driussi forcing defensive adjustments. Santa Fe arrives with solid domestic form and an unbeaten recent run but must overcome the aggregate deficit and River’s crowd advantage away from El Campín; multiple injuries including goalkeeper Andrés Mosquera further temper their away prospects in this single-match decider.